I have been using Google's new Chrome browser and am very impressed. Microsoft's MSDN site has never played well with Firefox, but it loads and runs fine in Chrome.
I look forward to the same developer support as one can find in Firefox. Firebug and Venkman would be great add-ons for Chrome.
IE is crap and always has been. It is purely painful to develop complex ASP.net applications with IE. Microsoft need to wake up and rewrite IE from the ground up, or just give up and phase out IE altogether.